General Cell Lines and Cell Cultures
ATCC Candida parapsilosis; B78
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Escherichia coli
Escherichia coli strain J53 pMG224 is a multidrug-resistant bacterium that produces extended spectrum beta-lactamase (ESBL) TEM-12. This strain is whole-genome sequenced and has applications in antimicrobial resistance research.
ATCC Pasteurella multocida; subsp. multocida
Pasteurella multocida subsp. multocida strain NCTC 10322 [W-9217] was isolated from a pig. This bacterial type strain is propagated aerobically in brain heart infusion medium.
ATCC Escherichia coli; Strain 1109131
Escherichia coli strain bMx# 1109131 is a clinical isolate from BioMerieux that can be used as a quality control strain for chromID Oxa 48 medium. This strain is resistant to ertapenem and the depositor claims that this strain is a carbapenemase producer (OXA-48).
ATCC Quantitative Genomic; DNA from; Proteus mirabilis
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
Eurofins Discoverx KILR MM-1R Cell Pool, 2 vials. (97-1045P052)
The KILR MM-1R cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of MM-1R cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Eurofins Discoverx CHO-K1 FFAR1 (GPR40) Gq Cell Line, 2 vials. (95-1005C2)
The FFAR1 (GPR40) Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. FFAs) based activation of FFAR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR1, a naturally Gq coupled GPCR. Upon activation of FFAR1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx CHO-K1 FFAR2 (GPR43) Gq Cell Line, 2 vials. (95-1002C2)
The FFAR2 (GPR43) Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. FFAs) based activation of FFAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR2, a naturally Gq coupled GPCR. Upon activation of FFAR2, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx CHO-K1 PTGER1 Gq Cell Line, 2 vials. (95-1003C2)
The PTGER1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin E2) based activation of PTGER1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER1, a naturally Gq coupled GPCR. Upon activation of PTGER1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx CHO-K1 F2RL1 Gq Cell Line, 2 vials. (95-1006C2)
The F2RL1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serine proteases, SLIGRL-NH2) based activation of F2RL1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses F2RL1, a naturally Gq coupled GPCR. Upon activation of F2RL1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC hTERT-HME1; Mammary Epithelium; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
ATCC Cryptococcus neoformans; WM626
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Enterococcus hirae
Type strain. Used in assay of folic acid and monensin. Note: ATCC 9790™ and ATCC 8043™ are the same.